Designs for Health customers can rest assured that when they order from us, they are receiving a top quality, professional-grade nutritional supplement formulated and manufactured according to our "Science First" approach. The Designs for Health "Science First" philosophy is most evident in our commitment to the research and science behind product development factors that are vital to the manufacture of a product that is superior in both quality and efficacy. Through our comprehensive approach and exceptionally high standards, we are able to ensure that our customers receive a consistently superior product every time they place an order
Annatto-E™ is a unique tocopherol-free, tocotrienols-only product, featuring tocotrienols sourced from the annatto tree. Annatto is the richest known source of tocotrienols, containing 100% tocotrienols (90% delta and 10% gamma isomers), with no tocopherols.
Commercial vitamin E supplements are typically rich in tocopherols and low or absent in tocotrienols; however, tocotrienol fractions have unique beneficial effects across a variety of tissues that make them desirable for supporting many aspects of health. Research indicates that tocopherols—especially alpha-tocopherol—may interfere with key therapeutic effects of tocotrienols, so it may be best to dose tocotrienols alone, without tocopherols.
Made with non-GMO ingredients.
Vitamin E is a family of eight separate but related molecules, including four tocopherols (alpha, beta, gamma, and delta) and four tocotrienols (alpha, beta, gamma, and delta). While alpha-tocopherol is found in most multivitamins and enriched foods, a growing base of evidence suggests that this popular vitamin E form not only lacks efficacy but actually interferes with the function and benefits of tocotrienols. Historically, vitamin E (alpha-tocopherol) has been known for its antioxidant effects, but tocotrienols have been found to be 40-60x more potent at protecting against cellular damage from harmful free radicals. This is due to their smaller and more flexible molecular structure, allowing tocotrienols – and in particular delta-tocotrienol – to be more easily incorporated into cell membranes. Annatto-E™ embodies the two most potent forms of vitamin E in delta-tocotrienol and gamma-tocotrienol and is free of alpha-tocopherol.
Tocotrienols are currently derived from three major sources: including rice, palm and annatto. Palm and rice tocotrienols contain 25-50% alpha-tocopherol, respectively, whereas annatto is essentially tocopherol-free. DFH carefully selected annatto as the most potent tocotrienol source for its Annatto-E™ products, which contains the proprietary DeltaGold® ingredient manufactured by American River Nutrition
Direction of Use: As a dietary supplement, take one capsules per day, or as directed by your health care practitioner.
Efficacious Dosage All of the clinical trials involving annatto tocotrienols to date utilized dosages between 125-600mg total tocotrienols per day which lead DFH to create a 300mg supplement so patients could easily take an efficacious dose. In addition a 150mg tocotrienol softgel is available as an antioxidant defense to lipid bio-membranes of the approximately 75 trillion cells contained in our bodies.