LOWER HOMOCYSTEINE: IMPROVE HEALTH*
Healthy, flexible blood vessels and blood flow is essential to:
1. Bring fuel and remove toxic waste from vital organs like your heart,
brain, intestines, muscles, kidneys, and liver.*
2. Keep blood vessels elastic and flexible for your full lifespan.*
3. Keep brain function clear and well-connected.*
4. Promote blood vessel health to avoid heart and blood vessel
hardening, Alzheimer’s senility, and thrombosis (platelet clumps and
clots that block blood flow) linked to stroke and heart attacks.
PERQUE Vessel Health Guard is the only natural and compre-hensive
solution to these problems.* It contains the fullest potency, safer, more
effective forms of:
1. B-6 (pharmaceutical purity pyridoxine)
2. B-12 (pharmaceutical purity hydroxocobalamin)
3. Folate (folacin, vitamin M)
4. Magnesium as ascorbate
All of these are transport-activated with mannitol and xylitol.This increases
rapid, full delivery to your brain and other critical body organs.*
If you want to keep the flow of blood to vital organs resilient as long as
possible, PERQUE Vessel Health Guard is your health protector.*
PERQUE Vessel Health Guard can make a significant difference in your
health.* The difference in 5-year mortality risk was 1,000%, or ten-fold, for
those with the highest homocysteine, and 100%, or two-fold, between the
higher and lower levels of homocysteine.*
HOMOCYSTEINE LEVEL: MARKER OF ADEQUATE NUTRIENT
INTAKE
Physicians use homocysteine levels to determine blood vessel health
status. When your homocysteine level is less than 6
Your blood vessels are healthier.
• Your risk of excessive blood clotting (thrombosis) in the brain (stroke) or heart (coronary occlusion, blocked heart artery) or major blood
vessel (arteriosclerosis or atherosclerosis) is lower.
Homocysteine levels tell if you have enough of certain nutrients that activate body catalysts (enzymes) essential for repairing blood vessels.
What about measuring B-12 levels? The standard (Schilling) B-12 test
measures the amount of B-12 in the serum.This does not correlate well
with the functional amount in your cells, which is why homocysteine
levels are functionally predictive of B-12 need. For example, all people
on “hypoglycemic” medications show a decrease in cellular B-12 and an
increase in homocysteine levels even though their standard B-12 tests
remain unchanged.*
DIFFERENT: PERQUE VESSEL HEALTH GUARD
PERQUE Vessel Health Guard is uniquely formulated with high-potency
nutritives to activate repair systems and lower homocysteine levels to their
healthier levels.* A useful target level for healthy homocysteine levels is
less than 6.
Additional benefits of PERQUE Vessel Health Guard include:
1. Reduction or elimination of homocystinuria (loss of sulfur compounds
in the urine).*
2. Reduction or elimination of excess methylmalonic acid (a marker of
ineffi-cient metabolism).*
3. Overall improvement in nutrient uptake by activating enzyme
catalysts needed for nutrient assimilation and action.*
4. Correction of dietary nutrient deficits.*
• Your blood vessels are healthier.
• Your risk of excessive blood clotting (thrombosis) in the brain (stroke) or heart (coronary occlusion, blocked heart artery) or major blood
vessel (arteriosclerosis or atherosclerosis) is lower.
Homocysteine levels tell if you have enough of certain nutrients that activate body catalysts (enzymes) essential for repairing blood vessels.
REFERENCES
1. Tawakol A, Migrino RQ, Aziz KS, Waitkowska J, Holmvang G, Alpert NM, Muller JE, Fischman AJ, Gewirtz H. High-dose folic acid acutely improves coronary
vasodilator function in patients with coronary artery disease. J Am Coll Cardiol 2005 May 17; 45(10):1580-4.
2. Vermeulen EG, Stehouwer CD, Twisk JW, van den Berg M, de Jong SC, Mackaay AJ, van Campen CM, Visser FC, Jakobs CA, Bulterjis EJ, Rauwerda JA. Effect of
homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial. Lancet
2000 Feb 12; 355(9203):517-22.
3. Refsum H, et. al. Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 2004 Jan;50(1):3-32.
4. Doshi S, et. al. Folate improves endothelial function in patients with coronary heart disease. Clin Chem Lab Med 2003; 41(11):1505-1512.
5. Weiss N, et. al. Influence of hyperhomocysteinemia on the cellular redox state--impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med
2003; 41(11):1455-1461.
6. Schroecksnadel K, et. al. Hyperhomocysteinemia and immune activation. Clin Chem Lab Med 2003; 41(11):1438-1443.
7. Ueland PM, Monsen AL. Hyperhomocysteinemia and B-vitamin deficiencies in infants and children. Clin Chem Lab Med 2003; 41(11):1418-1426.
8. Balk EM, et. al. Effects of statins on nonlipid serum markers associated with cardiovascular disease: a systematic review. Ann Intern Med 2003; 139(8):670-682.
9. Gilligan MA. Metformin and vitamin B-12 deficiency. Arch Intern Med. 2002;162:484-485
